Cartilage growth occurs through two different processes: interstitial growth and appositional growth. Interstitial growth occurs within the cartilage through mitotic division of the existing chondrocytes. … In appositional growth, new cartilage is laid down at the surface of the perichondrium.
What is Appositional growth?
Appositional growth is the increase in the diameter of bones by the addition of bony tissue at the surface of bones.
What cell is responsible for the appositional growth of cartilage?
chondrocytes Growth of cartilage is attributable to two processes: Interstitial growth which includes: Cell division of the chondrocytes.
Does appositional bone growth stop?
While bones are increasing in length, they are also increasing in diameter; growth in diameter can continue even after longitudinal growth ceases. This is called appositional growth. Osteoclasts, cells that work to break down bone, resorb old bone that lines the medullary cavity.
What is interstitial growth of cartilage?
Interstitial growth is the increase in the length of bones by the cartilage lengthening and is replacing by bone tissue while appositional growth is the increase in the diameter of bones by the addition of bony tissue at the surface of the pre-existing bone.
What is cartilage made from?
What is cartilage made of? Cartilage a strong and smooth substance made up of “chondrocytes,” or specialized cartilage cells, that produce a matrix of collagen, proteoglycans (a special type of protein) and other non-collagenous proteins.
What is the difference between ossification and calcification?
Ossification (or osteogenesis) in bone remodeling is the process of laying down new bone material by cells named osteoblasts. … Calcification is synonymous with the formation of calcium-based salts and crystals within cells and tissue. It is a process that occurs during ossification, but not necessarily vice versa.
What is Appositional growth cartilage grows in two ways appositional and interstitial appositional growth?
Cartilage grows in two ways, appositional and interstitial. What is appositional growth? … Chondrocytes in the lacunae divide and secrete matrix, allowing the cartilage to grow from within.
What is the ossification process?
bone formation, also called ossification, process by which new bone is produced. … Soon after the osteoid is laid down, inorganic salts are deposited in it to form the hardened material recognized as mineralized bone. The cartilage cells die out and are replaced by osteoblasts clustered in ossification centres.
What is responsible for Appositional growth?
In order to accommodate for increases in length, bones also need to increase in thickness. This type of growth, called appositional growth, happens when osteoblasts in the periosteum deposit new bone matrix layers onto already-formed layers of the outer surface of bone.
Where is perichondrium found?
Perichondrium is mainly found on the surfaces of elastic and hyaline cartilage, which can be found in multiple locations of the body, such as in the ears, nose, joints and ribs. Damage to the perichondrium is known as perichondritis, and can result from cartilage injuries.
What is chondroblasts and chondrocytes?
Chondroblasts are a type of cells found in the cartilage which are responsible for the cartilage development. Chondrocytes are a type of specialized cells found in cartilage which are responsible for cartilage maintenance.
When cartilage is produced at the epiphyseal side?
It is a layer of hyaline cartilage where ossification occurs in immature bones. On the epiphyseal side of the epiphyseal plate, cartilage is formed. On the diaphyseal side, cartilage is ossified, and the diaphysis grows in length. The epiphyseal plate is composed of four zones of cells and activity ((Figure)).
What cells are found in the periosteum?
The inner layer of the periosteum contains osteoblasts (bone-producing cells) and is most prominent in fetal life and early childhood, when bone formation is at its peak.
Where does Appositional growth occur?
This growth by adding to the free surface of bone is called appositional growth. Appositional growth can occur at the endosteum or peristeum where osteoclasts resorb old bone that lines the medullary cavity, while osteoblasts produce new bone tissue.
What does interstitial growth mean?
Interstitial growth is the process that adds or removes solid mass at locations inside a solid material. For this process to occur, there must be interstitial space within this material to allow atoms or molecules to bind to the underlying substrate.
Why is cartilage avascular?
Cartilage is avascular. Since there is no direct blood supply, chondrocytes receive nourishment via diffusion from the surrounding environment. The compressive forces that regularly act on cartilage also increase the diffusion of nutrients.
What is the function of Chondroblast?
Chondroblasts, located in the perichondrium, are cells that play an important role in the development of cartilage. By producing extracellular matrix, chondroblasts create the main component that provides structure and strength to cartilage.
Is cartilage alive?
Hyaline cartilage is found in the nose, ears, trachea, parts of the larynx, and smaller respiratory tubes. Fibrous cartilage has the fewest cells so it has the most intercellular space. Fibrous cartilage is found in the spine and the menisci. …
| Cartilage | |
|---|---|
| TA98 | A02.0.00.005 |
| TA2 | 381 |
| Anatomical terminology |
Where is your cartilage?
Cartilage is a connective tissue found in many areas of the body including: Joints between bones e.g. the elbows, knees and ankles. Ends of the ribs. Between the vertebrae in the spine.
What is cartilage short answer?
Cartilage is a flexible connective tissue found in many parts of the body. … It can bend a bit, but resists stretching. Its main function is to connect bones together. It is also found in the joints, the rib cage, the ear, the nose, the throat and between the bones of the back.
What hormones affect bone growth?
Three calcium-regulating hormones play an important role in producing healthy bone: 1) parathyroid hormone or PTH, which maintains the level of calcium and stimulates both resorption and formation of bone; 2) calcitriol, the hormone derived from vitamin D, which stimulates the intestines to absorb enough calcium and …
What causes calcifications in the body?
What causes calcification? Calcifications can be caused by inflammation or elevated levels of blood calcium, known as hypercalcemia. Calcification can be part of a normal healing response to musculoskeletal injuries.
What causes ossification?
HO occurs after other injuries, too. HO has been known to occur in cases of traumatic brain injury, stroke, poliomyelitis, myelodysplasia, carbon monoxide poisoning, spinal cord tumors, syringomyelia, tetanus, multiple sclerosis, post total hip replacements, post joint arthroplasty, and after severe burns.
Which is the best description of the interstitial growth of cartilage?
Which of the following statements best describes interstitial growth of cartilage? Chondrocytes in the lacunae divide and secrete matrix, allowing the cartilage to grow from within.
What is the epiphyseal plate?
The epiphyseal growth plate is the main site of longitudinal growth of the long bones. At this site, cartilage is formed by the proliferation and hypertrophy of cells and synthesis of the typical extracellular matrix. The formed cartilage is then calcified, degraded, and replaced by osseous tissue.
Where is the diaphysis?
The diaphysis is the tubular shaft that runs between the proximal and distal ends of the bone. The hollow region in the diaphysis is called the medullary cavity, which is filled with yellow marrow.
How does cartilage turn into bone?
Over time, most of this cartilage turns into bone, in a process called ossification. … Growth occurs when cartilage cells divide and increase in number in these growth plates. These new cartilage cells push older, larger cartilage cells towards the middle of a bone.
What is bone breakdown?
Resorption is the breakdown and assimilation of old bone in the cycle of bone growth. The process of resorption (remodeling) involves the removal of hard bone tissue by osteoclasts followed by the laying down of new bone cells by osteoblasts.
Why does ossification end?
This process continues throughout childhood and the adolescent years until the cartilage growth slows and finally stops. When cartilage growth ceases, usually in the early twenties, the epiphyseal plate completely ossifies so that only a thin epiphyseal line remains and the bones can no longer grow in length.
Graduated from ENSAT (national agronomic school of Toulouse) in plant sciences in 2018, I pursued a CIFRE doctorate under contract with Sun’Agri and INRAE in Avignon between 2019 and 2022. My thesis aimed to study dynamic agrivoltaic systems, in my case in arboriculture. I love to write and share science related Stuff Here on my Website. I am currently continuing at Sun’Agri as an R&D engineer.