Apigenin (Figure 2(a)) is a common flavonoid found in a range of plants, including chamomile (Matricaria recutita). The traditional use of chamomile tea as a treatment for insomnia and anxiety led to investigations of its active constituents, including apigenin.
How much apigenin is chamomile tea?
The amount of apigenin in chamomile teas varies, with some containing significantly more chamomile than others. Teas prepared from chamomile generally have between 0.8% to 1.2% apigenin content.
Is chamomile extract same as apigenin?
Optimum chamomile extracts contain about 50 percent alcohol. Normally standardized extracts contain 1.2% of apigenin which is one of the most effective bioactive agents. Aqueous extracts, such as in the form of tea, contain quite low concentrations of free apigenin but include high levels of apigenin-7-O-glucoside.
What is apigenin good for?
Apigenin has been used as a traditional medicine for centuries because of its physiological functions as an antioxidant and anti-inflammatory [6, 7], its role in lowering blood pressure [8], and its antibacterial and antiviral properties [9].
Where can I get apigenin?
Apigenin is a bioflavonoid compound (specifically a flavone) which is found in a wide variety of plants and herbs. It is very abundant in chamomile tea, and exerts anxiety-reducing effects when consumed in these high doses. At even higher doses, it may be sedative.
What is the best source of apigenin?
Apigenin is abundant in a variety of natural sources, including fruits and vegetables. The best sources of apigenin are parsley, chamomile, celery, vine-spinach, artichokes, and oregano, and the richest sources are in the dried forms [14, 15].
Is it OK to drink chamomile tea everyday?
How do I include chamomile tea in my diet? Chamomile tea can be consumed any time of day, but may be best consumed in the evening for its relaxing effects and potential sleep benefits. Or, if you have diabetes, it could be worth adding a cup after your meals.
Is apigenin safe to take?
Apigenin is considered safe, even at high doses, and no toxicity has been reported. Nonetheless, at high doses, it can trigger muscle relaxation and sedation [141].
How does apigenin work?
The research team conducted by Rehen demonstrated that apigenin works by binding to estrogen receptors, which affect the development, maturation, function, and plasticity of the nervous system.
Can chamomile cause anxiety?
Among alternative therapies for anxiety, chamomile has been used as a traditional herbal medicine for its calming effect. It is well tolerated and demonstrates pharmacological activity in animal models of anxiety. … Long Term Chamomile Therapy for Anxiety.
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Does apigenin help with anxiety?
Apigenin can reduce anxiety in sufficient doses, and thus may have neuroprotective and cognition-enhancing benefits. At lower doses, apigenin can suppress inflammation, which is a major hallmark of ageing. It also has potential as a potent anticancer supplement.
Does apigenin raise testosterone?
As shown in Fig. 1C, apigenin significantly increased testosterone production in mouse Leydig cells cultured in the medium containing 0.01 mM dbcAMP.
Does apigenin make you sleepy?
The plant extract contains apigenin, a chemical compound that induces sleepiness when it binds to the GABA receptors in the brain. GABA receptors are the same receptors that bind to benzodiazepines, which are commonly used as anti-anxiety drugs because they have a calming effect.
What is another name for apigenin?
Apigenin
| Names | |
|---|---|
| Other names Apigenine; Chamomile; Apigenol; Spigenin; Versulin; C.I. Natural Yellow 1 | |
| Identifiers | |
| CAS Number | 520-36-5 |
| 3D model (JSmol) | Interactive image |
How does chamomile affect the brain?
Apigenin, a flavonoid found in some spices and herbs, may improve neuron formation and strengthen connections between brain cells, researchers from D’Or Institute for Research and Education reported.
What herbs contain apigenin?
2 Apigenin. Apigenin is a flavonoid present in many vegetables and herbal spices including parsley, celery, basil, chamomile, cilantro, and oregano [32,33]. Plant flavonoids have been shown to decrease the risk of development of cancers and have been widely researched for chemoprevention.
Why is chamomile tea bad for you?
Most experts say chamomile is safe. It can cause drowsiness and, in large doses, vomiting. It also has the potential to trigger allergic reactions in people who are allergic to related plants in the daisy family, although such reactions are very rare.
Does chamomile help anxiety?
Chamomile (Matricaria chamomilla/Chamaemelum nobile) This daisy-like flower is synonymous with calm, making it among the most well-known stress-soothing teas. One 2016 study found that long-term use of chamomile extract significantly reduced moderate to severe symptoms of generalized anxiety disorder (GAD).
Is chamomile tea good for weight loss?
Packed with calcium and potassium, chamomile tea helps flush out the toxins from the body. This special brew is light on the stomach and relaxes it. It significantly reduces appetite, which definitely helps if you are someone trying to lose weight.
Is apigenin a sedative?
Among all the administered doses of apigenin, 0.6 mg/kg demonstrated a sedative effect (F4.35 = 2.657, p = 0.0490), resulting in a significant increase in the sleeping duration (Fig. 3).
Does apigenin lower blood pressure?
These data demonstrate that dietary apigenin decreases high blood pressure and improves endothelium-dependent relaxation in the DOCA-salt …
Graduated from ENSAT (national agronomic school of Toulouse) in plant sciences in 2018, I pursued a CIFRE doctorate under contract with Sun’Agri and INRAE in Avignon between 2019 and 2022. My thesis aimed to study dynamic agrivoltaic systems, in my case in arboriculture. I love to write and share science related Stuff Here on my Website. I am currently continuing at Sun’Agri as an R&D engineer.