Is hypercholesterolemia the same as high cholesterol?

Hypercholesterolemia is the term used to refer to a high blood cholesterol level. Cholesterol is a waxy substance that is produced by the liver and is a component of all cells found in the body. What causes hypercholesterolaemia?
Familial hypercholesterolaemia It’s caused by a gene alteration inherited from a parent, rather than an unhealthy lifestyle. People with familial hypercholesterolaemia have raised cholesterol from birth, which can lead to the early development of heart problems, such as atherosclerosis and CHD.

What is the life expectancy of someone with familial hypercholesterolemia?

Familial hypercholesterolemia FAQs A: Without treatment, the life expectancy of those with familial hypercholesterolemia can be reduced by approximately 15-30 years. However, in people with homozygous familial hypercholesterolemia, the life expectancy may only be 20 years or less. What is the best treatment for hypercholesterolemia?
Statins. Statins are usually the first hypercholesterolemia treatment used. Statins help reduce LDL levels by blocking a specific enzyme that’s necessary to produce cholesterol. Along with lowering LDL cholesterol, statins help prevent hardening of the arteries, which reduces the chances of a heart attack or stroke.

What should I eat if I have hypercholesterolemia?

Cholesterol and healthy eating

  • Plenty of vegetables, fruits and wholegrains.
  • A variety of healthy protein sources (especially fish and seafood), legumes (such as beans and lentils), nuts and seeds. …
  • Unflavoured milk, yoghurt and cheese. …
  • Healthy fat choices – nuts, seeds, avocados, olives and their oils for cooking.

What type of disorder is hypercholesterolemia?

Familial hypercholesterolemia is a genetic disorder. It is caused by a defect on chromosome 19. The defect makes the body unable to remove low density lipoprotein (LDL, or bad) cholesterol from the blood. This results in a high level of LDL in the blood.

Frequently Asked Questions(FAQ)

What is pure hypercholesterolaemia?

Pure or familial hypercholesterolemia is a condition in which a genetic anomaly causes high cholesterol levels. According to the Familial Hypercholesterolemia Foundation, an estimated 1 in 250 people worldwide have pure or familial hypercholesterolemia.

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Is hypercholesterolemia genetic?

Familial hypercholesterolemia (FH) is a genetic disorder that affects about 1 in 250 people and increases the likelihood of having coronary heart disease at a younger age.

Can I live a long life with FH?

FH has no cure, but it’s treatable. Life expectancy with FH is lower without treatment, but the sooner you receive a correct diagnosis and start medication, the better your outlook and life expectancy. FH is inherited from one or both of your parents and requires treatment with medication to lower your LDL cholesterol.

What is the best drink to lower cholesterol?

Best drinks to improve cholesterol

  1. Green tea. Green tea contains catechins and other antioxidant compounds that seem to help lower “bad” LDL and total cholesterol levels. …
  2. Soy milk. Soy is low in saturated fat. …
  3. Oat drinks. …
  4. Tomato juice. …
  5. Berry smoothies. …
  6. Drinks containing sterols and stanols. …
  7. Cocoa drinks. …
  8. Plant milk smoothies.

How do you reverse hypercholesterolemia?

Can FH be cured?

There isn’t a cure for FH but it can be treated. Treatment can reduce your risk of getting heart disease, having a heart attack or stroke, or needing other treatment. If you or your child is diagnosed with FH, speak with your doctor about the best treatment plan.

Do statins work for familial hypercholesterolemia?

The most common treatment for FH is statin drug therapy. Statin drugs work by blocking an enzyme that produces cholesterol in the liver and increases your body’s ability to remove cholesterol from the blood. They can lower your LDL cholesterol levels by 50 percent or more.

Can you be a carrier of familial hypercholesterolemia?

Familial hypercholesterolemia (LDLRAP1-related) is known as an autosomal recessive condition. For autosomal recessive conditions, if a person has a variation in one copy of their gene, they are a carrier.

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How is hypercholesterolemia diagnosed?

A diagnosis of hypercholesterolemia is based on routine blood analysis to check levels of “bad” cholesterol, which includes triglycerides and low-density lipoproteins (LDLs). The blood is also checked for the presence of high-density lipoprotein (HDLs) or “good” cholesterol.

What class of drugs is used to treat hypercholesterolemia?

Statins. These drugs block a substance the liver needs to make cholesterol. Examples include atorvastatin (Lipitor), fluvastatin (Lescol XL), lovastatin (Altoprev), pitavastatin (Livalo), pravastatin, rosuvastatin (Crestor) and simvastatin (Zocor). Ezetimibe (Zetia).

How does hypercholesterolemia affect the body?

With high cholesterol, you can develop fatty deposits in your blood vessels. Eventually, these deposits grow, making it difficult for enough blood to flow through your arteries. Sometimes, those deposits can break suddenly and form a clot that causes a heart attack or stroke.

What are the 3 foods to never eat?

20 Foods That Are Bad for Your Health

  1. Sugary drinks. Added sugar is one of the worst ingredients in the modern diet. …
  2. Most pizzas. …
  3. White bread. …
  4. Most fruit juices. …
  5. Sweetened breakfast cereals. …
  6. Fried, grilled, or broiled food. …
  7. Pastries, cookies, and cakes. …
  8. French fries and potato chips.

Is bread bad for cholesterol?

Try switching to whole-wheat or whole-grain varieties. These types of bread are also high in fiber, which can help lower your cholesterol. You might also try low-carbohydrate varieties of bread, but make sure that you check out the fat and fiber content on the food nutrition label before you make your choice.

Is canned tuna good for lowering cholesterol?

Replacing meats high in saturated fat with healthier options, like fish, is a smart tactic to improve cholesterol levels. Certain types of fish also provide heart-healthy omega-3 fatty acids. Good choices include salmon, albacore tuna (fresh and canned), sardines, lake trout and mackerel.

What is the most common cause of hypercholesterolemia?

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Mutations in the APOB, LDLR, LDLRAP1, or PCSK9 gene cause familial hypercholesterolemia. Changes in the LDLR gene are the most common cause of this condition. The LDLR gene provides instructions for making a protein called a low-density lipoprotein receptor.

At what age is familial hypercholesterolemia diagnosed?

Data from the FH Foundation’s CASCADE (Cascade Screening for Awareness and Detection) FH registry demonstrated that the diagnosis of FH occurred at a mean age of 50 years, by which time more than one third of the patients with FH had already experienced an atherosclerotic cardiovascular disease (ASCVD) event.

Can you lower genetic high cholesterol without medication?

People can naturally lower their cholesterol levels through dietary and lifestyle changes. Replacing trans fats with monounsaturated and polyunsaturated fats can help lower levels of LDL cholesterol and raise levels of HDL cholesterol.

Is familial hypercholesterolemia life threatening?

Familial hypercholesterolemia (FH) is a common life-threatening genetic condition that causes high cholesterol. Untreated, FH leads to early heart attacks and heart disease.

What is Type 2 hypercholesterolemia?

Familial hypercholesterolemia (FH), also known as familial hyperlipoproteinemia type 2 or Fredrickson class 2a hyperlipidemia, is an autosomal dominant-inherited genetic disorder that leads to elevated blood cholesterol levels. Typically, the patient inherits only 1 of the defective genes, making him heterozygous.

Is hypercholesterolemia a chronic condition?

The study classifies the following as chronic diseases: cardiovascular disease, hypertension, diabetes mellitus, hypercholesterolemia, asthma, COPD, and previous cancer (6).

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