In what is described as “the therapeutic or threshold range,” Ketchum reports the autonomic effects of BZ to consist of the following: “dryness of the mouth, decreased gastric motility, inhibition of sweating, peripheral vasodilation, a slightly increased heart beat and blood pressure, and a mild elevation in body …

What is QNB ligand?

3-Quinuclidinyl benzilate (QNB) (1-azabicyclo[2.2. 2]oct-3-yl hydroxy(diphenyl)acetate; BZ) is a potent, atropine-like glycolic acid ester that blocks muscarinic receptors in the CNS and PNS (Spencer, 2000). … Early studies demonstrated QNB was a potent and selective ligand for muscarinic receptors.

What is BZ agent?

SUMMARY. Agent BZ (3-quinuclidinyl benzilate) is an odorless, environmentally stable, white crystalline powder with anticholinergic activity. Once considered a potential incapacitating agent for military applications, it is currently used as a pharmacological tool (a muscarinic antagonist known as QNB).

Is BZ a nerve agent?

BZ is a nerve agent temporarily disabling a person. The effect is achieved within 30-60 minutes and lasts up to four days, Lavrov said. Maryland’s Edgewood Arsenal experimented with BZ, along with LSD, THC, ketamine, opioids and other drugs on hundreds of military personnel and civilians into the mid-1970s.

How harmful is BZ?

It is described by the U.S. Army as a “central nervous system depressant.” It can “disrupt the high integrative functions of memory, problem solving, attention, and comprehension. A relatively high dose produces toxic delirium, destroying the individual’s ability to perform any military task.”

Is BZ a drug?

3-quinuclidinyl benzilate (BZ) is a centrally acting synthetic anticholinergic agent. BZ is used as a hallucinogenic and incapacitating CWA. It is about 25 times more potent than atropine and has a very long duration of action.

What are the effects of sarin gas?

Initial symptoms following exposure to sarin are a runny nose, tightness in the chest, and constriction of the pupils. Soon after, the person will have difficulty breathing and they will experience nausea and drooling. As they continue to lose control of bodily functions, they may vomit, defecate, and urinate.

What is phosgene gas used for?

What phosgene is. Phosgene is a major industrial chemical used to make plastics and pesticides. At room temperature (70°F), phosgene is a poisonous gas. With cooling and pressure, phosgene gas can be converted into a liquid so that it can be shipped and stored.

What is lewisite used for?

Lewisite was produced in 1918 to be used in World War I, but its production was too late for it to be used in the war. Lewisite has been used only as a chemical warfare agent. It has no medical or other practical use. Lewisite is not found naturally in the environment.

Was nerve gas used in Vietnam?

The U.S. military used nerve gas on a mission to kill Americans who defected during the Vietnam War, CNN and Time magazine said Sunday in a joint report. The so-called Operation Tailwind was approved by the Nixon White House as well as the CIA, the report said, quoting as its main source retired Adm.

How do you pronounce Quinuclidinyl Benzilate?

What is vomit gas?

Medical Definition of vomiting gas : chloropicrin in aerosol form for use especially as a war gas or crowd-control agent.

What is Bz in military terms?

Bravo Zulu. This is a naval signal, conveyed by flaghoist or voice radio, meaning well done; it has also passed into the spoken and written vocabulary. It can be combined with the negative signal, spoken or written NEGAT, to say NEGAT Bravo Zulu, or not well done.

What is BZ Aurora?

Bz is the solar wind’s magnetic orientation in the up/down direction. Although an Aurora can happen with a positive Bz, a negative Bz is generally better. A negative Bz helps the solar wind grab the earth’s magnetic field which can more easily lead to an Aurora. So a negative Bz is good. The more negative the better.

Did the US use sarin gas?

Entitled Valley of Death, the report claimed that US air support had used sarin nerve gas against opponents, and that other war crimes had been committed by US forces during Tailwind. … Operation Tailwind.

Date 11–13 September 1970
Result U.S.-South Vietnamese victory

Who invented sarin gas?

Sarin, along with other nerve agents like Tabun and Soman, was first produced in Germany’s famous I.G. Farben factory in October 1938 by chemist Gerhard Schrader and his team—quite by accident.

Was sarin gas used in ww2?

The Nazis Developed Sarin Gas During WWII, But Hitler Was Afraid to Use It. Even as his Nazi regime was exterminating millions in the gas chambers, Adolf Hitler resisted calls to use the deadly nerve agent against his military adversaries. Hitler certainly had the opportunity to use sarin in World War II.

How do you cook phosgene?

Production. Industrially, phosgene is produced by passing purified carbon monoxide and chlorine gas through a bed of porous activated carbon, which serves as a catalyst: CO + Cl2 → COCl2 (ΔHrxn = −107.6 kJ/mol) This reaction is exothermic and is typically performed between 50 and 150 °C.

How much phosgene is fatal?

[7] Lethal dose of phosgene in humans is approximately 500 ppm/min of exposure or exposure at 3 ppm for 170 min is equally as fatal as exposure at 30 ppm for 17 min.

What is the common name of phosgene?

phosgene, also called carbonyl chloride, a colourless, chemically reactive, highly toxic gas having an odour like that of musty hay, used in making organic chemicals, dyestuffs, polycarbonate resins, and isocyanates for making polyurethane resins.

What is the treatment for lewisite?

Treatment. British anti-lewisite, also called dimercaprol, is the antidote for lewisite. It can be injected to prevent systemic toxicity, but will not prevent injury to the skin, eyes, or mucous membranes. Chemically, dimercaprol binds to the arsenic in lewisite.

Has lewisite been used?

Although chemical weapons were not used in major combat during World War II, the Japanese used lewisite and mustard gas in China during most of the war years.

What does inhaling chlorine gas do to you?

Acute exposure at high levels causes dyspnea, violent cough, nausea, vomiting, lightheadedness, headache, chest pain, abdominal discomfort, and corneal burns, in addition to the same symptoms of low-level acute exposure. Chronic exposure to chlorine gas can lead to chest pain, cough, sore throat, and hemoptysis.