Concordance, as used in genetics, usually means the presence of the same trait in both members of a pair of twins. … Discordant rates that are higher than concordant rates express the influence of the environment on twin traits.
How do we interpret concordance rates?
Formally, the concordance rate is the percent of cases in which both members of a pair have a particular attribute. In a study of the relative influence of genes and environment on a mental illness, for example, the attribute is the particular mental illness, and the pairs studied are usually twins.
What is an example of concordance?
An example of a concordance is two friends agreeing to go into business in a certain way. An example of a concordance is a list showing how many times the word Jesus shows up in the Bible and in what passages. (genetics) The presence of a given trait in both members of a pair of twins.
What is the concordance rate of diabetes?
The observed rates of concordance for Type II diabetes at 1, 5, 10, and 15 years follow-up were 17, 33, 57, and 76%, respectively. The concordance rate for any abnormality of glucose metabolism (either Type II diabetes or impaired glucose tolerance) at 15 years follow-up was 96%.
What does a concordance rate of 1 mean?
Concordance rates means the. probability of one twin having the disorder if the other already has it expressed as a percentage. In a twin study, MZ (identical) and DZ (non-identical) twins are compared. Whilst MZ twins have a.
What do concordance means?
1 : an alphabetical index of the principal words in a book or the works of an author with their immediate contexts. 2 : concord, agreement.
What is concordance in statistics?
From Wikipedia, the free encyclopedia. In statistics, the concordance correlation coefficient measures the agreement between two variables, e.g., to evaluate reproducibility or for inter-rater reliability.
What does a concordance rate indicate quizlet?
A concordance rate indicates. the percentage of twin pairs or other pairs of relatives who exhibit the same disorder.
What is a concordance study?
In genotyping studies where DNA is directly assayed for positions of variance (see SNP), concordance is a measure of the percentage of SNPs that are measured as identical.
What’s another word for concordance?
In this page you can discover 14 synonyms, antonyms, idiomatic expressions, and related words for concordance, like: accord, meeting of the minds, agreement, concurrence, consonance, rapport, concord, harmony, unity, agree and dictionary.
How do you write a concordance?
What is concordance in a sentence?
Definition of Concordance. agreement; accord. Examples of Concordance in a sentence. 1. The newest scientific data was in concordance with the last test and also the one before that.
What is more common dizygotic and monozygotic?
Monozygotic twins share 100% of each other’s genes. Dizygotic twins share only 50%. This is the same genetic similarity as siblings conceived and born at different times.
Is type 1 diabetes purely genetic?
We are also unsure about whether type 1 diabetes is hereditary or not. While 90 per cent of people who develop type 1 diabetes have no relative with the condition, genetic factors can pre-dispose people to developing type 1 diabetes. Certain gene markers are associated with type 1 diabetes risk.
Can a Type 1 diabetic have twins?
CONCLUSIONS Risk of type 1 diabetes at 3 years is high for initially multiple and single autoantibodypositive identical twins and multiple autoantibodypositive nonidentical twins. Genetic predisposition, age, and male sex are significant risk factors for development of positive autoantibodies in twins.
What are MZ and DZ twins?
Monozygotic (MZ) twins arise from a single zygote, and have always been thought to inherit identical genomic sequences [1], whereas dizygotic (DZ) twins arise from two different zygotes and, just like siblings, share on average 50% identity in their genomic sequence.
What is the concordance rate for MZ twins?
For the total twin population of 354 pairs, we obtained a probandwise concordance rate of 25.4% in MZ twin pairs and 5.4% in DZ pairs.
What is pairwise concordance?
The pairwise concordance rate indicates the proportion of pairs in which both members are affected, whereas the proband concordance rate states the proportion of affected individuals among co-twins of previously defined index cases.
What is a concordant result?
Concordant readings: If readings have been taken several times and the readings are identical, or close to each other, then they are described as concordant.
What is online concordance?
A concordance gives a list of several words, phrases, or distributed structures along with immediate contexts from a corpus or text.
What is concordance in prescribing?
Concordance is a new approachto the prescribing and taking of medicines. It is an agreement reached after negotiation between a patient and a healthcare professional that respects the beliefs and wishes of the patient in determining whether, when, and how medicines are to be taken.
What is agreement in statistics?
agreement-statistics. Agreement is the degree to which two raters, instruments, etc, give the same value when applied to the same object.
What is the purpose of a concordance?
A Biblical concordance is a reference tool that provides an alphabetic listing of Biblical words along with their Biblical references. This allows one to study the various uses of words throughout scripture. Some concordances are organized according to the original Biblical languages (e.g., Hebrew and Greek).
What is a discordant variable?
7. 3. A pair of observations is concordant if the subject who is higher on one variable is also higher on the other variable. A pair of observations is discordant if the subject who is higher on one variable is lower on the other variable.
What is the concordance rate for schizophrenia in monozygotic twins?
[2] Analyzing classic studies of the genetics of schizophrenia done as early as in 1930s, Fischer concludes that a concordance rate for psychosis of about 50% in monozygotic twins seems to be a realistic estimate, which is significantly higher than that in dizygotic twins of about 1019%.
When concordance rates are higher among monozygotic twins than dizygotic twins this indicates what?
Terms in this set (6) The higher the concordance rate, the more similar pairs of persons are within a sample. When concordance rates are higher among MZ than DZ twins, this indicates that the basis for the trait is partly genetic.
Does research support the thinking that there is a schizophrenia gene?
Genetic studies strongly suggest that many different genes increase the risk of developing schizophrenia, but that no single gene causes the disorder by itself. It is not yet possible to use genetic information to predict who will develop schizophrenia.
How do you use concordance?
What is the best concordance?
Best Sellers in Christian Bible Concordances
- #1. The New Strong’s Expanded Exhaustive …
- #2. Nelson’s Illustrated Bible Dictionary: New and …
- #3. Nueva Concordancia Strong Exhaustiva. …
- #4. NKJV, Reference Bible, Center-Column Giant …
- #5. New Strong’s Concise Concordance of the Bible. …
- #6. The Strongest NASB Exhaustive …
- #7. …
- #8.
What is the difference between a concordance and a lexicon?
As nouns the difference between lexicon and concordance is that lexicon is the vocabulary of a language while concordance is agreement; accordance; consonance.
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