Abstract. Breast hamartomas are rare, benign, tumor-like nodules composed of glandular, adipose and fibrous tissue. The hamartoma was first described in 1971 as a lipofibroadenoma, fibroadenolipoma or adenolipoma, based on the predominant component of the breast tissue.
Should breast hamartomas be removed?
Surgical excision is the definitive treatment. Hamartomas have the same malignant potential as normal breast tissue, unless greater than 6 cm, and thus do not require any additional treatment than one would for adenoma or other benign lesions.
How is breast hamartoma diagnosed?
Mammography shows a uniformly dense mass. When a mammographic round or oval mass with a heterogeneous internal density and a radiolucent halo becomes a compressible heterogeneous mass which is surrounded by an echogenic or echolucent halo on sonography, breast hamartoma may be diagnosed.
What is hamartoma in pathology?
A hamartoma (from Greek hamartia, meaning “fault, defect,” and -oma, denoting a tumor or neoplasm) is a benign (noncancerous) tumorlike malformation made up of an abnormal mixture of cells and tissues found in areas of the body where growth occurs.
Can breast hamartomas become cancerous?
Are Hamartomas worrisome in terms of possible breast cancer? No, usually a breast hamartoma is a benign tumor, but, in rare instances, they can develop simultaneously with coincidental breast epithelial cell malignancy within the same lesion.
Do breast hamartomas hurt?
Small hamartomas are usually painless and only present as slow-growing breast masses that do not attach to the underlying structure of the breasts. However, large hamartomas may be painful due to compression of the normal breast tissue.
How rare is a breast hamartoma?
Mammary hamartoma is a rare benign lesion accounting for approximately 4.8% of all benign breast masses. It is often underdiagnosed and therefore is underreported mostly due to lack of awareness of the characteristic clinical and histological features.
Are hamartomas benign?
A hamartoma is a local malformation made up of an abnormal mixture of cells and tissue. Although most hamartomas are benign, they cause morbidity by various mechanisms such as; infection, infarction, pressure/obstruction, hemorrhage/anemia, fracture, neoplastic transformation.
How common are hamartomas?
Incidence. Many people have never heard of hamartomas, but they are relatively common tumors. Lung hamartomas are the most common type of benign lung tumor, and benign lung tumors are relatively common. 6 Breast hamartomas are responsible for roughly 5 percent of benign breast masses.
Is papilloma a benign tumor?
Papillomas are benign growths. This means that they do not grow aggressively and they do not spread around the body. The growths only form in certain types of tissue, although these tissues occur all over the body. Papillomas are often known as warts and verrucae when they reach the skin.
What is a hamartoma?
(HA-mar-TOH-muh) A benign (not cancer) growth made up of an abnormal mixture of cells and tissues normally found in the area of the body where the growth occurs.
Can a breast hematoma burst?
More rarely, hematoma can result from breast biopsy. Rarely, a breast hematoma can also occur spontaneously due to a rupture of blood vessels in the breast, especially in persons with coagulopathy or after long-term use of blood-thinning drugs such as aspirin or ibuprofen.
What causes a breast hamartoma?
What causes hamartomas to grow? The exact cause of hamartoma growths is unknown, and cases are usually sporadic. These benign growths are associated with other conditions, including: Pallister-Hall syndrome, a genetic disorder that affects bodily development and may cause you to have extra fingers or toes.
What is the difference between hamartoma and benign tumor?
The line of demarcation between hamartomas and benign neoplasms is often unclear, since both lesions can be clonal. A hamartoma, however, contrary to a neoplasm, shows a self-limited growth.
Are hamartomas hereditary?
PTEN hamartoma tumor syndrome is hereditary, which means it can be passed from parents to their children.
Are hamartomas congenital?
A hamartoma is a congenital tumor composed of tissues normally found in the involved area, in contrast to a choristoma, which is a congenital tumor composed of tissues not normally present in the involved area.
How big can hamartoma get?
Pulmonary hamartomas grow slowly, and most of them are smaller than 4 cm, although they may reach 10 cm in diameter. The tumors are usually solitary, although multiple tumors in the Carney triad have been reported.
Is hamartoma a neoplasm?
A hamartoma is a mostly benign, local malformation of cells that resembles a neoplasm of local tissue but is usually due to an overgrowth of multiple aberrant cells, with a basis in a systemic genetic condition, rather than a growth descended from a single mutated cell (monoclonality), as would typically define a …
What is neoplasm disease?
Neoplastic disease. A neoplasm is an abnormal growth of cells, also known as a tumor. Neoplastic diseases are conditions that cause tumor growth — both benign and malignant. Benign tumors are noncancerous growths. They usually grow slowly and can’t spread to other tissues.
Can ultrasound detect fibroadenoma?
A breast ultrasound can help your doctor determine whether a breast lump is solid or filled with fluid. A solid mass is more likely a fibroadenoma; a fluid-filled mass is more likely a cyst.
Is Choristoma malignant?
What is the outcome for patients with choristoma? The lesions are benign with little risk of malignant transformation.
What does fat necrosis look like on ultrasound?
Fat necrosis can present as lipid cysts, coarse calcifications, focal asymmetries, microcalcifications, or spiculated masses. The mammographic features reflect the amount of fibrosis. If minimal fibrosis occurs, the mass appears as a radiolucent mass or as an oil cyst [1] (Figs.
What does ultrasound Pash look like?
On ultrasound, PASH often appears as an oval, circumscribed, hypoechoic mass. On magnetic resonance imaging, PASH usually has progressive (Type 1) enhancement, and high-signal slit-like spaces may be seen on T2-weighted and short tau inversion recovery (STIR) images.
Are adenomas always benign?
Adenomas are generally benign or non cancerous but carry the potential to become adenocarcinomas which are malignant or cancerous. As benign growths they can grow in size to press upon the surrounding vital structures and leading to severe consequences.
Can hamartomas metastasize?
Endobronchial hamartoma, the most common benign lung tumor, is located in the bronchus, and it easily mimics lung cancer or bronchial metastasis.
Graduated from ENSAT (national agronomic school of Toulouse) in plant sciences in 2018, I pursued a CIFRE doctorate under contract with Sun’Agri and INRAE in Avignon between 2019 and 2022. My thesis aimed to study dynamic agrivoltaic systems, in my case in arboriculture. I love to write and share science related Stuff Here on my Website. I am currently continuing at Sun’Agri as an R&D engineer.