Acinic cell carcinoma (ACC) is a low-grade malignant salivary neoplasm that constitutes approximately 17% of primary salivary gland malignancies. In the head and neck region, the parotid gland is the predominant site of origin and women are usually more frequently diagnosed than men.
How bad is acinic cell carcinoma?
IMPORTANCE. Acinic cell carcinoma is a rare salivary neoplasm that is generally associated with a good prognosis, although a subset of patients develops local and distant recurrences. Given the rarity of the disease, factors to identify patients at risk for recurrences or decreased survival are not clearly defined.
Can acinic cell carcinoma be cured?
While surgical excision is usually done to treat acinic cell carcinoma, modern research has examined the possibility of radiotherapy as a treatment procedure. This is due to the treatment hypothesis that parotid cancer patients would generally demonstrate survival with adjuvant radiotherapy.
Can acinic cell carcinoma spread?
Although acinic cell carcinomas rarely metastasize, they have a high tendency to recur locally if they are incompletely excised. We describe a patient with acinic cell tumor arising in the parotid gland, with metastases to the contralateral orbit, submandibular salivary gland, and submandibular lymph node.
What does Acinic mean?
Definitions of acinic. adjective. pertaining to one of the small sacs (as in a compound gland)
How fast do salivary gland tumors grow?
Doctors also give salivary gland tumors a grade of 1 to 3 that measures how fast the cancer cells seem to be growing: Grade 1 (low-grade) cancers have the best chance of being cured. They grow slowly and don’t look much different than normal cells. Grade 2 cancers grow moderately fast.
What is acinic cell?
Acinic cell carcinoma (ACC) is a low-grade malignant salivary neoplasm that constitutes approximately 17% of primary salivary gland malignancies. In the head and neck region, the parotid gland is the predominant site of origin and women are usually more frequently diagnosed than men.
Are all cancers carcinomas?
Not all cancers are carcinoma. Other types of cancer that aren’t carcinomas invade the body in different ways. Those cancers begin in other types of tissue, such as: Bone.
What is the most common parotid tumor?
The most common malignant tumor is mucoepidermoid carcinoma, followed by acinic cell carcinoma and adenoid cystic carcinoma. It is also important to remember that the parotid gland is a common site for metastases from squamous cell carcinomas arising in the skin of the head and neck.
Why is it called clear cell carcinoma?
Clear cell renal cell carcinoma is also called conventional renal cell carcinoma. Clear cell renal cell carcinoma is named after how the tumor looks under the microscope. The cells in the tumor look clear, like bubbles.
Is Mucoepidermoid carcinoma rare?
Reports of mucoepidermoid carcinomas of the subglottis are not common. Women are more commonly affected than men (3:2), and the mean age at onset is in the 5th decade of life. MEC is also the most common salivary gland malignancy in children.
What is parotid surgery?
Your Recovery Parotidectomy (say puh-rawt-ih-DEK-tuh-mee) is the removal of the parotid glands, located below the ears. They make saliva, which enters the mouth through a tube (duct) near the back teeth. Most tumours that grow in the parotid glands are benign, which means they aren’t cancer.
What is a granular tumor?
Listen to pronunciation. (GRAN-yoo-lur sel TOO-mer) A rare type of soft tissue tumor that usually begins in Schwann cells (cells that hold nerve cells in place). It can occur anywhere in the body, but it usually occurs in or under the skin of the head and neck (especially the mouth or tongue).
What is a parotid tumor?
Parotid tumors are abnormal growths of cells (tumors) that form in the parotid glands. The parotid glands are two salivary glands that sit just in front of the ears on each side of the face. Salivary glands produce saliva to aid in chewing and digesting food.
What is warthin tumor?
Warthin tumor is a benign tumor of the salivary gland. The first symptom is usually a painless, slow-growing bump in front of the ear, on the bottom of the mouth, or under the chin. Warthin tumors may increase in size over time, but few become cancerous.
Do cell phones cause salivary gland tumors?
The use of wireless phones was not associated with an overall increased risk of salivary gland tumours, odds ratio 0.8, 95% confidence interval 0.4-1.5.
How long does it take to recover from salivary gland surgery?
Your Recovery A saliva duct is a tube that carries saliva from the gland into the mouth. The area below your jaw may be sore for several days after your surgery. The area also may be slightly swollen or bruised. It will probably take 1 to 2 weeks for the cut (incision) to heal.
What percentage of salivary gland tumors are malignant?
About 80 percent of salivary gland tumors start in these glands. About 75 percent of these tumors are benign (usually a type called pleomorphic adenomas) and 25 percent are malignant.
What is acinar cell carcinoma?
Acinar cell carcinoma, also known as acinic cell carcinoma, is a malignant epithelial neoplasm composed of cells with morphological resemblance to acinar cells and with evidence of exocrine enzyme production by the neoplastic cells.
What does Adenolymphoma mean?
: a benign tumor of the salivary glands and usually of the parotid gland that is characterized by columnar epithelial cells lining the cystic spaces and by the increase of lymphoid tissue in the stroma Adenolymphomas usually occur in men over the age of 50 years, and are occasionally bilateral.
What is secretory carcinoma?
Secretory carcinoma is a very rare subtype of breast carcinoma. These tumors are generally associated with a favorable prognosis, although having triple-negative phenotype (estrogen receptor (ER), progesterone receptor (PR) negative and c-erbB2 (HER2) negative).
What is the difference between carcinoma and adenocarcinoma?
Carcinoma is the most common form of cancer. It starts in the epithelial tissue of your skin or internal organs. Adenocarcinoma is a subtype of carcinoma. It grows in the glands that line the insides of your organs.
Which is worse squamous cell carcinoma or adenocarcinoma?
In all patients and in pN0 patients, patients with squamous cell carcinoma showed significantly poorer overall survival than those with adenocarcinoma, but there were no statistically significant differences in the recurrence-free proportion between the two histologic types.
What’s the difference between squamous cell carcinoma and adenocarcinoma?
Carcinomas are divided into two major subtypes: adenocarcinoma, which develops in an organ or gland, and squamous cell carcinoma, which originates in the squamous epithelium. Adenocarcinomas generally occur in mucus membranes and are first seen as a thickened plaque-like white mucosa.
Should a parotid tumor be removed?
Treatment Surgery is recommended for almost all parotid gland tumors, whether cancerous or benign. Although most tumors grow slowly and are non-cancerous, they will often continue to grow and occasionally can become cancerous. Treatment of a parotid tumor generally requires removing the parotid gland (parotidectomy).
Do parotid tumors grow quickly?
They tend to grow quickly and are often found in minor salivary glands. Undifferentiated carcinomas: This is a cancer group that includes large cell undifferentiated carcinoma, small cell undifferentiated carcinoma as well as lymphoepithelial carcinoma. They’re high-grade cancers that do tend to spread.
Can a parotid tumor grow back?
Recurrent parotid tumors unfortunately regrow after initial treatment, requiring further surgery. Repeat surgery increases both the chances of facial paralysis and facial cosmetic deformities.
Graduated from ENSAT (national agronomic school of Toulouse) in plant sciences in 2018, I pursued a CIFRE doctorate under contract with Sun’Agri and INRAE in Avignon between 2019 and 2022. My thesis aimed to study dynamic agrivoltaic systems, in my case in arboriculture. I love to write and share science related Stuff Here on my Website. I am currently continuing at Sun’Agri as an R&D engineer.