What is acinic cell?

Acinic cell carcinoma (ACC) is a low-grade malignant salivary neoplasm that constitutes approximately 17% of primary salivary gland malignancies. In the head and neck region, the parotid gland is the predominant site of origin and women are usually more frequently diagnosed than men.

How bad is acinic cell carcinoma?

IMPORTANCE. Acinic cell carcinoma is a rare salivary neoplasm that is generally associated with a good prognosis, although a subset of patients develops local and distant recurrences. Given the rarity of the disease, factors to identify patients at risk for recurrences or decreased survival are not clearly defined.

Can acinic cell carcinoma be cured?

While surgical excision is usually done to treat acinic cell carcinoma, modern research has examined the possibility of radiotherapy as a treatment procedure. This is due to the treatment hypothesis that parotid cancer patients would generally demonstrate survival with adjuvant radiotherapy.

Can acinic cell carcinoma spread?

Although acinic cell carcinomas rarely metastasize, they have a high tendency to recur locally if they are incompletely excised. We describe a patient with acinic cell tumor arising in the parotid gland, with metastases to the contralateral orbit, submandibular salivary gland, and submandibular lymph node.

What does Acinic mean?

Definitions of acinic. adjective. pertaining to one of the small sacs (as in a compound gland)

What is acinar cell carcinoma?

Acinar cell carcinoma, also known as acinic cell carcinoma, is a malignant epithelial neoplasm composed of cells with morphological resemblance to acinar cells and with evidence of exocrine enzyme production by the neoplastic cells.

What is acinic cell carcinoma of the parotid gland?

Acinic cell carcinoma (ACC) is a low-grade malignant salivary neoplasm that constitutes approximately 17% of primary salivary gland malignancies. In the head and neck region, the parotid gland is the predominant site of origin and women are usually more frequently diagnosed than men.

Are all cancers carcinomas?

Carcinoma. Carcinoma refers to a malignant neoplasm of epithelial origin or cancer of the internal or external lining of the body. Carcinomas, malignancies of epithelial tissue, account for 80 to 90 percent of all cancer cases. Epithelial tissue is found throughout the body.

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How fast do salivary gland tumors grow?

Doctors also give salivary gland tumors a grade of 1 to 3 that measures how fast the cancer cells seem to be growing: Grade 1 (low-grade) cancers have the best chance of being cured. They grow slowly and don’t look much different than normal cells. Grade 2 cancers grow moderately fast.

Why is it called clear cell carcinoma?

Clear cell renal cell carcinoma is also called conventional renal cell carcinoma. Clear cell renal cell carcinoma is named after how the tumor looks under the microscope. The cells in the tumor look clear, like bubbles.

What is parotid surgery?

Surgery to remove a tumor in the deep lobe — or in both the deep and superficial lobes — is called a total parotidectomy. The two lobes are separated by the facial nerve. Treating parotid gland tumors requires great precision on the part of your surgical team because the facial nerve is nearby.

Is Mucoepidermoid carcinoma rare?

Reports of mucoepidermoid carcinomas of the subglottis are not common. Women are more commonly affected than men (3:2), and the mean age at onset is in the 5th decade of life. MEC is also the most common salivary gland malignancy in children.

What is the most common parotid tumor?

The most common malignant tumor is mucoepidermoid carcinoma, followed by acinic cell carcinoma and adenoid cystic carcinoma. It is also important to remember that the parotid gland is a common site for metastases from squamous cell carcinomas arising in the skin of the head and neck.

What is a parotid tumor?

Parotid tumors are abnormal growths of cells (tumors) that form in the parotid glands. The parotid glands are two salivary glands that sit just in front of the ears on each side of the face. Salivary glands produce saliva to aid in chewing and digesting food.

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What is warthin tumor?

Warthin tumor is a benign tumor of the salivary gland. The first symptom is usually a painless, slow-growing bump in front of the ear, on the bottom of the mouth, or under the chin. Warthin tumors may increase in size over time, but few become cancerous.

Is acinar cell carcinoma an adenocarcinoma?

Acinar cell carcinomas (ACCs) are rare neoplasms of the exocrine pancreas, comprising less than 1% of primary pancreatic tumors. The ACCs are distinct from the more common pancreatic ductal adenocarcinomas.

What does acinar predominant mean?

IMAs were divided into lepidic-predominant and acinar-predominant IMA, according to the growth pattern of tumor cells. Lepidic-predominant and acinar-predominant IMAs are defined as having a lepidic or an acinar pattern of more than 50%.

What do pancreatic cells do?

The pancreatic acini are clusters of cells that produce digestive enzymes and secretions and make up the bulk of the pancreas. The endocrine function of the pancreas helps maintain blood glucose levels, and the structures involved are known as the pancreatic islets, or the islets of Langerhans.

Is adenoid cystic carcinoma slow growing?

Adenoid cystic carcinoma (ACC) of salivary glands is a slow-growing malignant tumor, characterized by wide local infiltration, perineural spread, a propensity to local recurrence and late distant metastasis.

What is carcinoma ex pleomorphic adenoma?

Carcinoma ex pleomorphic adenoma (CXPA) is a carcinoma arising from a primary or recurrent benign pleomorphic adenoma. It often poses a diagnostic challenge to clinicians and pathologists. The entity is difficult to diagnose preoperatively. Pathological assessment is the gold standard for making the diagnosis.

What is secretory carcinoma?

Secretory carcinoma is a very rare subtype of breast carcinoma. These tumors are generally associated with a favorable prognosis, although having triple-negative phenotype (estrogen receptor (ER), progesterone receptor (PR) negative and c-erbB2 (HER2) negative).

What do carcinomas look like?

At first, a basal cell carcinoma comes up like a small pearly bump that looks like a flesh-colored mole or a pimple that doesn’t go away. Sometimes these growths can look dark. Or you may also see shiny pink or red patches that are slightly scaly. Another symptom to watch out for is a waxy, hard skin growth.

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Is carcinoma hereditary?

It’s estimated that between 3 and 10 in every 100 cancers are associated with an inherited faulty gene. Cancers caused by inherited faulty genes are much less common than those caused by other factors, such as ageing, smoking, being overweight and not exercising regularly, or not eating a healthy, balanced diet.

Can carcinoma be cured?

Most cases of squamous cell carcinoma can be cured when found early and treated properly. Today, many treatment options are available, and most are easily performed at a doctor’s office.

How common are salivary gland tumors?

Salivary gland cancers are not very common, making up less than 1% of cancers in the United States. They occur at a rate of about 1 case per 100,000 people per year in the United States.

What does a salivary gland tumor feel like?

A lump or swelling on or near your jaw or in your neck or mouth. Numbness in part of your face. Muscle weakness on one side of your face. Persistent pain in the area of a salivary gland.

Do salivary gland tumors hurt?

In most cases, salivary gland cancer causes a painless lump on a salivary gland. If a salivary gland tumor is malignant, you are more likely to experience other symptoms, including: Weakness or numbness in the face, neck, jaw or mouth. Persistent pain in the face, neck, jaw or mouth.