Concanavalin A (ConA) is a lectin (carbohydrate-binding protein) originally extracted from the jack-bean (Canavalia ensiformis). … It is also used to purify glycosylated macromolecules in lectin affinity chromatography, as well as to study immune regulation by various immune cells.
What is Coca-Cola Cona?
Coke One North America (CONA) is a platform that provides each of the 12 largest Coca-Cola Company North American bottling partners with tools they need to collaborate as one company. CONA Services manages the solution specifically to support bottlers in North America.
What is Coke One North America?
Coke One North America (CONA) is elevating the North American bottling business by equipping local bottlers with state-of-the-art technology solutions for business process optimization.
How many bottlers does Coca-Cola have?
Coca-Cola and its nearly 225 independent bottling partners employ more than 700,000 people, helping bring economic opportunity to local communities worldwide. Due to the strength of this unique system, we are able to create global reach with local focus.
What is con a response?
Concanavalin A (Con A)-induced Lymphocyte Proliferation – Measurement of human lymphocyte proliferative responses to various stimuli is a fundamental technique used to assess their biological status and functions. … Both T and B lymphocytes are stimulated by PWM, while only T cells are stimulated by PHA and Con A.
What sugar does con a bind to?
The carbohydrate-binding specificity of Con A has been studied in great detail by every conceivable technique. It binds d-glucose, d-fructose, d-mannose, N-acetyl-d-glucosamine and related monosaccharides [3,8], The -anomer of d-mannose is the monosaccharide most complementary to the Con A sugar binding site.
How do they make Coke Zero?
We sweeten Coke Zero Sugar in our bottles and cans with a blend of aspartame and acesulfame potassium (or Ace-K). Together, they create a great taste with zero sugar and zero calories. Yes. Diet Coke in our bottles and cans is sweetened with aspartame.
Why did Coke buy bottlers?
But Coke and its main rival, PepsiCo, have faced a slide in the demand for carbonated beverages in recent years. Reacquiring bottling operations is meant to give Coke greater flexibility in adapting to consumer tastes, like a move toward juice drinks and water.
Why is Coke refranchising?
Refranchising of bottling operations: Coca-Cola is refranchising many of its bottling operations in a bid to move away from the capital intensive and low margin business of bottling, and focus more on the concentrate business as the consumption of carbonated drinks continues to slow down, especially in developed …
What Coke does to your body?
Regular consumption of these ingredients in the high quantities you find in Coke and other processed foods and drinks can lead to higher blood pressure, heart disease, diabetes, and obesity.
What do Mitogens do?
A mitogen is a peptide or small protein that induces a cell to begin cell division: mitosis. … The mechanism of action of a mitogen is that it triggers signal transduction pathways involving mitogen-activated protein kinase (MAPK), leading to mitosis.
What does concanavalin A stain?
Con A can be used to selectively stain the cell surface of live cells, and withstand fixation and permeabilization. When cells are fixed and permeabilized before staining, fluorescent lectins stain both cell surface and organelles in the secretory pathway.
What is Phytohemagglutinin used for?
One of the mitogens, phytohemagglutinin (PHA), has been widely used for the purpose of mitotic stimulation to human lymphocytes, and several different types of PHA, such as PHA-P, M, W and others were compared on their ability to induce mitoses and presented by other workers (5-10).
Does tomato have lectin?
Lectins are naturally occurring proteins that are found in most plants. Some foods that contain higher amounts of lectins include beans, peanuts, lentils, tomatoes, potatoes, eggplant, fruits, and wheat and other grains. Lectins serve a protective function for plants as they grow.
Does lectin cause leaky gut?
For those who eat a lot of raw, lectin-rich foods vegetarians or those following a plant-rich diet, for example the higher lectin intake and the resulting gastrointestinal distress like nausea, diarrhea and bloating can weaken the delicate gut lining, triggering leaky gut syndrome, system-wide inflammation and …
Is concanavalin a drug?
Concanavalin A (ConA), a lectin with mannose specificity that can induce acute hepatic inflammation, was tested for its therapeutic effect against hepatoma. ConA is cytotoxic or inhibitory to hepatoma cells, which is mediated by the autophagic pathway through mitochondria.
Why is aspartame bad?
Dozens of studies have linked aspartame the world’s most widely used artificial sweetener to serious health problems, including cancer, cardiovascular disease, Alzheimer’s disease, seizures, stroke and dementia, as well as negative effects such as intestinal dysbiosis, mood disorders, headaches and migraines.
Is Coke Zero worse than coke?
Coke Zero, which has recently been rebranded as Coca-Cola Zero Sugar, is marketed as a healthier version of the original sugar-sweetened beverage, Coca-Cola Classic.
Is Splenda aspartame?
Sucralose and aspartame are artificial sweeteners. Fillers help mellow their intense sweetness and add a few calories. Splenda does not contain aspartame, though it has fillers that are also found in aspartame-based sweeteners.
Why did Coke and Pepsi buy bottlers?
Historically, they believed that their greatest growth would come from fountain drinks. Thus, they sold off the bottling rights, which turned out to be a good move in keeping the companies asset-light and less capital-intensive. The beverage companies just produce the concentrates and syrups.
Does Pepsi do its own bottling?
Pepsi Bottling Ventures does not own the formulas to most of the beverages we sell. Pepsi Bottling Ventures purchases the exclusive rights to make, sell, and distribute the beverages within its territory from the syrup companies, such as PepsiCo, Inc., which owns the formula rights.
Why did Coke spin off CCE?
CCE itself was spun off from Coca-Cola in 1986 as a way to boost Coke’s profit margins and balance sheet by separating the capital-intensive, low-margin bottling business into a different company. CCE shareholders will own 48 percent of the new entity, with CCIP’s shareholders owning 34 percent.
What does Refranchise mean?
Each of these brands leverage refranchising. Refranchising is the selling or conversion of company-owned stores to existing or new franchisees. Refranchising is not a new concept but is an increasingly popular trend in the restaurant industry.
Does Coca Cola own its bottling plants?
The CocaCola Company does not own, manage or control most local bottling companies. In our concentrate operations, The Coca-Cola Company typically generates net operating revenues by selling concentrates and syrups to authorized bottling partners.
Graduated from ENSAT (national agronomic school of Toulouse) in plant sciences in 2018, I pursued a CIFRE doctorate under contract with Sun’Agri and INRAE in Avignon between 2019 and 2022. My thesis aimed to study dynamic agrivoltaic systems, in my case in arboriculture. I love to write and share science related Stuff Here on my Website. I am currently continuing at Sun’Agri as an R&D engineer.