What is Nitrophenolate?

From Wikipedia, the free encyclopedia. Nitrophenols are compounds of the formula HOC6H5 x(NO2)x. The conjugate bases are called nitrophenolates. Nitrophenols are more acidic than phenol itself.

Is 3 nitrophenol soluble in ethanol?

Soluble in water (30 mg/ml), ether, alcohol, acetone, and ethanol (700 mg/ml).

What is the melting point of 3 Nitrophenol?

93°C to 98°C Specifications

Density 1.49
Boiling Point 194°C (70mmHg)
Quantity 10g
Melting Point 93°C to 98°C
Flash Point >100°C (212°F)

What is the structure of nitro phenol?


PubChem CID 6947
Structure Find Similar Structures
Chemical Safety Laboratory Chemical Safety Summary (LCSS) Datasheet
Molecular Formula C6H5NO3
Synonyms 2-NITROPHENOL o-Nitrophenol 88-75-5 Phenol, 2-nitro- 2-Hydroxynitrobenzene More…

What is P-nitrophenol PNP?

p-Nitrophenyl Phosphate (PNPP) is a non-proteinaceous, non-specific substrate used to assay protein, alkaline and acid phosphatases. … The assay can be used for the quick analysis of the protein phosphatase activity under any non-standard conditions.

What are Nitrophenols used for?

4-Nitrophenol is used to manufacture drugs, fungicides, insecticides, and dyes and to darken leather.

Is 2-nitrophenol soluble in water?

2-Nitrophenol is slightly soluble in cold water, but 4-nitrophenol is moderately soluble in cold water.

How do you prepare m-nitrophenol?

m-Nitrophenol can be prepared by diazotizing m-nitroaniline and subsequently heating with a large volume of water;1 by treating benzene with mercury nitrate and nitric acid in an atmosphere of carbon dioxide;2 and by boiling m-nitrophenetole (from phenacetin by nitration, hydrolysis, and diazotization in alcohol) with …

How do you dissolve p-nitrophenol?

P-Nitrophenol is soluble in organic solvents like ethanol, Methanol, Chloroform , ethyl acetate etc. Two of the good solvents of p-nitrophenol are: acetonitrile & dibutyl ether. p-nitrophenol is easily soluble in most of the organic solvents as mentioned by some senior researcher earlier.

Why is P nitrophenol yellow?

pH indicator The yellow color of the 4-nitrophenolate form (or 4-nitrophenoxide) is due to a maximum of absorbance at 405 nm (ε = 18.3 to 18.4 mM 1 cm 1 in strong alkali).

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What is the pKa of 4 Nitrophenol?

3D Structure for HMDB0001232 (4-Nitrophenol)

Property Value Source
pKa (Strongest Acidic) 7.07 ChemAxon
pKa (Strongest Basic) -7.1 ChemAxon
Physiological Charge 0 ChemAxon
Hydrogen Acceptor Count 3 ChemAxon

Why is para more acidic than meta?

Select the correct answer below: The nitro group in the meta position is closer to the hydroxyl group. As a result, it can abstract a proton and reduce the acididy of the phenol more than a nitro group in the para position, which is the farthest position from the hydroxyl group.

What is pKa of PNP?

pKa (Strongest Acidic) 7.04.

Is 4 nitrophenol toxic?

Poisonous by ingestion and moderately toxic by skin contact. … Acute (short-term) inhalation or ingestion of 4-nitrophenol in humans causes headaches, drowsiness, nausea, and cyanosis (blue color in lips, ears, and fingernails). Contact with eyes causes irritation in humans.

How you will separate O nitrophenol and p-nitrophenol?

i.e. non-volatile and o – nitrophenol is steam distillable . i.e. volatile. Hence the answer is C ; The mixture of o – nitrophenol and p – nitrophenol can be separated by steam distillation but o – nitrophenol is steam volatile.

What is the pH of PNP?

around pH 7.00 Due to many analytical determinations of enzymatic activities, the release of pNP is carried around pH 7.00.

What is the pH of phenol?

around 5 – 6 Properties of phenol as an acid The pH of a typical dilute solution of phenol in water is likely to be around 5 – 6 (depending on its concentration). That means that a very dilute solution isn’t really acidic enough to turn litmus paper fully red. Litmus paper is blue at pH 8 and red at pH 5.

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What color of light does PNP absorb?

It has a pKa value of 7.08 and depending on its pH, it can be protonated or deprotonated. At a pH of 4, PNP is fully protonated meaning it doesn’t absorb light that is visible to the human eye. At a pH of 10, PNP is fully deprotonated meaning it does absorb light with a wavelength in the blue spectrum.

Is Ortho Nitrophenol colorless?

ONPG, ortho-nitrophenyl-galactoside, is a colorless compound cleaved by β-galactosidase to yield the soluble compound, ortho-nitrophenol (ONP), which absorbs light at a maximum wavelength of 420 nm and is yellow in color.

Is para nitro phenol soluble NaHCO3?

in p-nitrophenol there is no hydrogen bonding so it is more acidic than phenol and react with base like as NaOH and NaHCO3 . hence it is soluble .

What color is p-nitrophenol?

Colorless Yellow More videos on YouTube

Indicator Color at pH incidated
Below 6 6-9
p-nitrophenol Colorless Yellow
Phenolphthalein Colorless Colorless
(mixture of phenolphthalein and p-nitrophenol) Colorless Yellow

Is o-nitrophenol an acid?

Thus, o – and p – nitrophenols are more acidic than m – nitrophenol. Among o- and p nitrophenols, o- nitrophenol is little less acidic than p-nitrophenol due to intramolecular H-bonding which makes loss of a proton little more difficult.

Is 2-nitrophenol polar?

1, onitrophenol; 2, nitrobenzene; 3, o-nitroanisole; 4, phenol; 5, m-nitrophenol. hypothesis 3) fits, o nitrophenol. They are also moderately polar compounds.

Is 2-nitrophenol toxic?

Water insoluble. 2-NITROPHENOL is a yellow, crystalline material, moderately toxic, low melting point (45° C). When heated to decomposition it emits toxic fumes of oxides of nitrogen.

How do I make a meta nitro benzene?

How will you synthesize m- nitrophenol from nitrobenzene?

Dissolve 6.7g (0.04 mol) of m-dinitrobenzene in 50 ml of hot methanol in a 250-ml round-bottomed flask and add, with shaking, the previously prepared methanolic solution of sodium hydrogen sulphide. Attach a reflux condenser and boil the mixture for 20 min; ignore any further sodium carbonate which may precipitate.

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How is meta nitroaniline prepared from Meta dinitrobenzene?

Principle: m-nitroaniline unlike o and p-nitroaniline cannot be prepared by direct nitration of Aniline. It has therefore to be prepared by reducing only one of the nitro groups in m-Dinitrobenzene. This selective reduction can be achieved by boiling an aqueous suspension of m-Dinitrobenzene with sodium disulphide.

What is p-nitrophenol used for in spectrophotometry?

p-Nitrophenyl Phosphate (PNPP) is a non-proteinaceous, non-specific substrate used to assay protein, alkaline and acid phosphatases. … The assay can be used for the quick analysis of the protein phosphatase activity under any non-standard conditions.

Why o-nitrophenol has lower boiling point than p-nitrophenol?

P-nitrophenol shows intermolecular hydrogen bonding. So it has higher bonding point. Whereas o-nitrophenol shows intra molecular H-bonding hence lower boiling point.

Why p-nitrophenol is stronger acid than phenol?

Para-nitrophenol is more acidic than phenol due to the presence of an electron withdrawing group, -NO2 group, which enhances the acidic strength of the compound by stabilizing the phenoxide ion and the ortho- and para-positions in the benzene ring becomes electron rich.

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