What is the CCLE?

CCLE (Common Collaboration and Learning Environment) is a campus-wide service that makes collaboration possible across schools, divisions, and departments across UCLA. CCLE is based upon Moodle, an open-source learning management system (LMS), and is administered upon multiple servers.

What is cancer cell line encyclopedia?

The Cancer Cell Line Encyclopedia is a database of gene expression, genotype, and drug sensitivity data for human cancer cell lines. Citation(s) Barretina, J et al. (2012) The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.

What is human cancer cell lines?

Cancer cells that keep dividing and growing over time, under certain conditions in a laboratory. Cancer cell lines are used in research to study the biology of cancer and to test cancer treatments.

Can CCLE track activity?

Live logs provide a real-time report of activity on your CCLE site for the previous hour. This will give the same information as “Logs”, described above, but will automatically update every 60 seconds. You may also pause the live updates by clicking the Pause Live Updates button.

Why does UCLA use CCLE?

Provide students and faculty with a single workspace that integrates information, resources, and outputs; Give UCLA the ability to deploy campus-wide IT innovations created locally at UCLA or within the higher education community; Integrate with emerging tools in pedagogy and educational technology.

What is GEPIA2?

GEPIA2: an enhanced web server for large-scale expression profiling and interactive analysis.

What is a cell line in cell culture?

Cell line. (Science: cell culture) a cell line is a permanently established cell culture that will proliferate indefinitely given appropriate fresh medium and space. lines differ from cell strains in that they have escaped the Hayflick limit and become immortalised.

Are all cell lines cancerous?

There are various immortal cell lines. Some of them are normal cell lines (e.g. derived from stem cells). Other immortalised cell lines are the in vitro equivalent of cancerous cells.

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Where do cancer cell lines come from?

It was derived from cervical cancer cells taken from Henrietta Lacks in 1951 (2). Since then, hundreds of cancer cell lines have been established and propagated either in vitro as monolayer cultures or in vivo as xenografts in mice (3).

Can you get cancer from working with cancer cell lines?

There is almost no chance that any direct infection or transmission of cancer can occur to a lab worker. However, there is a chance that any adventitial or cancer-associated microorganisms present in the cell culture can be transmitted to the user.

Can CCLE detect screenshots?

edit: the answer is no unless you have to use respondus or another plugin.

Can CCLE track IP address?

The CCLE site collects non-personal information to improve functionality and content and to monitor performance, including the Internet protocol (IP) address used to connect your computer to the Internet; your browser type and version, operating system, and platform; and the full Uniform Resource Locators (URLs) used …

How do I stop cheating on online trivia?

How to Prevent Cheating on a Quiz

  1. Question Pooling. Select questions from a pool at random, so each person gets a different quiz.
  2. Randomize Question Display. Shuffle the questions, so the questions are never presented in the same order. …
  3. Shuffle the answer options inside a question. …
  4. Add a Time limit.

How do you use UCLA CCLE?

Getting Started

  1. Logging in. Your course website is located at http://ccle.ucla.edu. …
  2. Find your course website. After logging in, you will need to find your course website. …
  3. Start editing your course website. …
  4. Change the layout of your course. …
  5. Upload a file. …
  6. Add a link. …
  7. Add text and images onto a section page.

What LMS does UCLA use?

CCLE stands for the Common Collaboration and Learning Environment, and it’s a project that multiple parts of UCLA’s campus participate in.

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What is UCSC Xena?

UCSC Xena (http://xena.ucsc.edu (link is external)) is a web-based, visual exploration tool for all modes of multi-omic data and associated annotations. Xena has several seminal cancer datasets pre-loaded and ready for visualization including TCGA, ICGC, GTEx and more.

How do you cite GTEX data?

The format of the sample ID is GTEX-[donor ID]-[tissue site ID]-SM-[aliquot ID]. The donor ID (e.g. GTEX-14753) should be used to link between the various RNA-seq and genotype samples that come from the same donor. The tissue site ID (e.g. 1626) mostly refers to the tissue site.

What cell line means?

Cell line is a general term that applies to a defined population of cells that can be maintained in culture for an extended period of time, retaining stability of certain phenotypes and functions. Cell lines are usually clonal, meaning that the entire population originated from a single common ancestor cell.

What is the difference between cell line and cell strain?

Using this nomenclature system, a continuous cell line is a population of cells that has undergone a genetic transformation, resulting in indefinite growth potential. … A cell strain is a subpopulation of a cell line that has been positively selected from the culture, by cloning or some other method.

Why do we use CHO cells?

CHO cells became popular because they have a low chromosome number and were used to study genetics. … These characteristics have made CHO cells the most important cell line for the production of therapeutic proteins including humanized antibodies.

How do you make a cell line immortal?

The most well-known immortality gene is Telomerase (hTERT). A ribonucleoprotein, telomerase is able to extend the DNA sequence of telomeres, thus abating the senescence process and enabling the cells to undergo infinite cell divisions.

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Which cell is immortal in human body?

HeLa cells HeLa cells, like other cell lines, are termed immortal in that they can divide an unlimited number of times in a laboratory cell culture plate as long as fundamental cell survival conditions are met (i.e. being maintained and sustained in a suitable environment).

Are all cancers carcinomas?

Carcinoma. Carcinoma refers to a malignant neoplasm of epithelial origin or cancer of the internal or external lining of the body. Carcinomas, malignancies of epithelial tissue, account for 80 to 90 percent of all cancer cases. Epithelial tissue is found throughout the body.

How many human cancer cell lines are there?

Introduction to NCI-60 Human Cancer Cell Lines The 60 created cell lines represent nine human cancers: breast, central nervous system, colon, kidney, leukemia, lung, melanoma, ovary, and prostate.

How do you establish a cancer cell line?

To establish cell lines from explants, tumor tissue is cut into smaller pieces (2 mm3) and plated into 6-well plates that have been coated with fetal bovine serum. It is then supplemented with essential nutrients for optimal growth.

Why are cancer cell lines useful?

Cell lines derived from cancer cells are frequently used in research, including use as a model to understand cancer and to identify potential new treatments. These cell lines, such as the HeLa cells, are “immortalized” and so continuously grow.