What is the meaning of acinic cell carcinoma?

Acinic cell carcinoma is a malignant tumor representing 2% of all salivary tumors. 90% of the time found in the parotid gland, 10% intraorally on buccal mucosa or palate. The disease presents as a slow growing mass, associated with pain or tenderness in 50% of the cases. Often appears pseudoencapsulated.

Can acinic cell carcinoma be cured?

(21) reported that the cure rate decreased from 89% at 5 years to 56% at 20 years. Spiro et al. (20) reported the survival rate to be 76% at 5 years, 63% at 10 years, and 55% at 15 years.

How bad is acinic cell carcinoma?

IMPORTANCE. Acinic cell carcinoma is a rare salivary neoplasm that is generally associated with a good prognosis, although a subset of patients develops local and distant recurrences. Given the rarity of the disease, factors to identify patients at risk for recurrences or decreased survival are not clearly defined.

What is the meaning of acinic?

Definitions of acinic. adjective. pertaining to one of the small sacs (as in a compound gland)

What is acinic cell carcinoma of the parotid gland?

Acinic cell carcinoma (ACC) is a low-grade malignant salivary neoplasm that constitutes approximately 17% of primary salivary gland malignancies. In the head and neck region, the parotid gland is the predominant site of origin and women are usually more frequently diagnosed than men.

Are all cancers carcinomas?

Not all cancers are carcinoma. Other types of cancer that aren’t carcinomas invade the body in different ways. Those cancers begin in other types of tissue, such as: Bone.

Can acinic cell carcinoma spread to brain?

Acinic cell carcinoma represents approximately 5% to 17% of all salivary gland cancers1 , 2 and can very rarely arise from the lacrimal gland. Spiro et al7 reported a distant metastasis rate of 12%, mainly to lung, bone, and brain.

How fast do salivary gland tumors grow?

Doctors also give salivary gland tumors a grade of 1 to 3 that measures how fast the cancer cells seem to be growing: Grade 1 (low-grade) cancers have the best chance of being cured. They grow slowly and don’t look much different than normal cells. Grade 2 cancers grow moderately fast.

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Is Mucoepidermoid carcinoma rare?

Reports of mucoepidermoid carcinomas of the subglottis are not common. Women are more commonly affected than men (3:2), and the mean age at onset is in the 5th decade of life. MEC is also the most common salivary gland malignancy in children.

What is the most common parotid tumor?

The most common malignant tumor is mucoepidermoid carcinoma, followed by acinic cell carcinoma and adenoid cystic carcinoma. It is also important to remember that the parotid gland is a common site for metastases from squamous cell carcinomas arising in the skin of the head and neck.

What is a parotid tumor?

Parotid tumors are abnormal growths of cells (tumors) that form in the parotid glands. The parotid glands are two salivary glands that sit just in front of the ears on each side of the face. Salivary glands produce saliva to aid in chewing and digesting food.

Why is it called clear cell carcinoma?

Clear cell renal cell carcinoma is also called conventional renal cell carcinoma. Clear cell renal cell carcinoma is named after how the tumor looks under the microscope. The cells in the tumor look clear, like bubbles.

Is adenoid cystic carcinoma slow growing?

Adenoid cystic carcinoma (ACC) of salivary glands is a slow-growing malignant tumor, characterized by wide local infiltration, perineural spread, a propensity to local recurrence and late distant metastasis.

What is secretory carcinoma?

Secretory carcinoma is a very rare subtype of breast carcinoma. These tumors are generally associated with a favorable prognosis, although having triple-negative phenotype (estrogen receptor (ER), progesterone receptor (PR) negative and c-erbB2 (HER2) negative).

What is epithelial myoepithelial carcinoma?

INTRODUCTION. Epithelial-myoepithelial carcinoma (EMC) is a rare biphasic tumor of the salivary gland. It is generally composed of variable proportions of two cell types: An inner layer of duct lining cells and an outer layer of clear cells, which typically form double-layered duct-like structures.

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What do carcinomas look like?

At first, a basal cell carcinoma comes up like a small pearly bump that looks like a flesh-colored mole or a pimple that doesn’t go away. Sometimes these growths can look dark. Or you may also see shiny pink or red patches that are slightly scaly. Another symptom to watch out for is a waxy, hard skin growth.

Are carcinomas always malignant?

Carcinoma is a malignancy that begins in the skin or in tissues that line or cover internal organs. Sarcoma is a malignancy that begins in bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue.

Can carcinoma be cured?

Most cases of squamous cell carcinoma can be cured when found early and treated properly. Today, many treatment options are available, and most are easily performed at a doctor’s office.

What is warthin tumor?

Warthin tumor is a benign tumor of the salivary gland. The first symptom is usually a painless, slow-growing bump in front of the ear, on the bottom of the mouth, or under the chin. Warthin tumors may increase in size over time, but few become cancerous.

What is parotid surgery?

Surgery to remove a tumor in the deep lobe — or in both the deep and superficial lobes — is called a total parotidectomy. The two lobes are separated by the facial nerve. Treating parotid gland tumors requires great precision on the part of your surgical team because the facial nerve is nearby.

What is salivary duct carcinoma?

Salivary duct carcinoma (SDC) is a highly malignant tumor that is histologically similar to ductal carcinoma of the breast. This article presents the clinicopathologic features of 15 patients with SDC arising in the salivary glands. The majority of patients were male and aged 65 years or older.

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What percentage of salivary gland tumors are malignant?

About 80 percent of salivary gland tumors start in these glands. About 75 percent of these tumors are benign (usually a type called pleomorphic adenomas) and 25 percent are malignant.

How many types of salivary gland cancers are there?

About 7 out of 10 salivary gland tumors start here. Most of these tumors are benign (not cancer), but the parotid glands still are where most malignant (cancerous) salivary gland tumors start. The submandibular glands are smaller and are below the jaw.

Should a parotid tumor be removed?

Treatment Surgery is recommended for almost all parotid gland tumors, whether cancerous or benign. Although most tumors grow slowly and are non-cancerous, they will often continue to grow and occasionally can become cancerous. Treatment of a parotid tumor generally requires removing the parotid gland (parotidectomy).

Is Mucoepidermoid carcinoma serious?

Prognosis. Generally, there is a good prognosis for low-grade tumors, and a poor prognosis for high-grade tumors, however recent research have found reoccurring low grade tumors also have a poor prognosis.

What is the treatment of Mucoepidermoid carcinoma?

Surgical resection is the mainstay of treatment for all grades of MEC. Local resection of the cancer is considered sufficient treatment for low-grade tumors. High-grade tumors are generally treated with surgical excision with wide margins followed by postoperative radiotherapy.

Can a parotid tumor grow back?

Recurrent parotid tumors unfortunately regrow after initial treatment, requiring further surgery. Repeat surgery increases both the chances of facial paralysis and facial cosmetic deformities.