2-Chlorobutanoic acid;hydrochloride | C4H8Cl2O2 – PubChem.
Why is 2-Chlorobutanoic acid stronger than 3-Chlorobutanoic acid?
In 2-chlorobutanoic acid substituent chloro is closer to the C-O-H(no. of sigma bond is less from C-O-H to Cl) bond and -I effect (polarization of bond) is higher as compared to 3-chlorobutanoic acid. Therefore H remove easily as proton in 2-chlorobutanoic acid and hence it is stronger acid.
What is pKa value of 3-Chlorobutanoic acid?
Accuracy of Prediction of pKa (Home)
| Molecule | Exp. pKa | Calc’d pKa |
|---|---|---|
| 3-Chlorobutanoic acid | 4.05 | 4.28 |
| 3-Chlorophenol | 8.78 | 8.96 |
| 3-Chloropropanoic acid | 3.98 | 4.29 |
| 4-Chlorobutanoic acid | 4.53 | 4.71 |
What is the structure of 3-Chlorobutanoic acid?
3-chlorobutanoic acid
| Compound number: | MolPort-001-792-261 |
|---|---|
| IUPAC traditional: | 3-chlorobutanoic acid |
| SMILES: | CC(Cl)CC(O)=O |
| InChI key: | XEEMVPPCXNTVNP-UHFFFAOYSA-N |
| Molecular formula: | C4H7ClO2 |
What is the Ka of 4 Chlorobutanoic acid?
| C4H6O8 | Dihydroxytartaric acid | 1.92 |
| C4H7CIO2 | 2-Chlorobutanoic acid | 2.86 |
| C4H7CIO2 | 3-Chlorobutanoic acid | 4.05 |
| C4H7CIO2 | 4-Chlorobutanoic acid | 4.52 |
| C4H7NO2 | 4-Cyanobutanoic acid | 2.42 |
What is the pKa of 3 chlorobenzoic acid?
3.9 3D Structure for HMDB0001544 (m-Chlorobenzoic acid)
| Property | Value | Source |
|---|---|---|
| logP | 10( 2.23 ) g/L | ChemAxon |
| logS | 10(- 2.3 ) g/L | ALOGPS |
| pKa (Strongest Acidic) | 3.9 | ChemAxon |
| Physiological Charge | -1 | ChemAxon |
Is 4 Chlorobutanoic acid a strong acid?
Yes, according to me 2-chlorobutanoic acid is a stronger acid than 3-chlorobutanoic acid. … In 3-chlorobutanoic acid, the effect is weaker as the chlorine atom is farther away………….
Why is 2 Fluorobutanoic acid stronger than 3 Fluorobutanoic acid?
In 2-Fluorobutanoic acid substituent Fluoro is closer to the C-O-H(no. of sigma bond is less from C-O-H to F) bond and -I effect (polarization of bond) is higher as compared to 3-Fluorobutanoic acid. Therefore H remove easily as proton in 2-Fluorobutanoic ​acid and hence it is stronger acid.
Why benzoic acid is stronger than acetic acid?
Benzoic acid itself is a somewhat stronger acid than acetic acid. The carboxyl group of benzoic acid is attached to an sp2-hybridized carbon which is more electronegative and electron-withdrawing than the sp3-hybridized carbon attached to acetic acid. … The opposite effect occurs with electron donating substituents.
What is the Iupac name of the following compound 3 Chlorobutanoic acid?
(3S)-3-Chlorobutanoic acid
| PubChem CID | 642200 |
|---|---|
| Structure | Find Similar Structures |
| Molecular Formula | C4H7ClO2 |
| Synonyms | 25139-77-9 AC1LD4HV (3S)-3-chlorobutanoic acid (S)-(-)-3-chlorobutanoic acid 3-chloro-butyric acid More… |
| Molecular Weight | 122.55 |
What is the pKa of chloroacetic acid?
2.87 Ionization Constants of Heteroatom Organic Acids
| Common Name | Formula | pKa |
|---|---|---|
| chloroacetic acid | ClCH2CO2H | 2.87 |
| citric acid | C(OH)(CH2CO2H)2CO2H | 3.13 4.76 6.40 |
| formic acid | HCO2H | 3.75 |
| ascorbic acid | 4.17 11.6 |
What is the pKa of formic acid?
Formic acid, mp 8.3°C [3], bp 100.8°C (at 101.3 kPa) [4], is a colorless, clear, corrosive liquid with a pungent odor. It is the strongest unsub- stituted alkyl carboxylic acid (pKa 3.74).
What is the condensed structural formula of ethanol?
Classification of Alcohols
| Condensed Structural Formula | Class of Alcohol | Common Name |
|---|---|---|
| CH 3CH 2OH | primary | ethyl alcohol |
| CH 3CH 2CH 2OH | primary | propyl alcohol |
| (CH 3) 2CHOH | secondary | isopropyl alcohol |
| CH 3CH 2CH 2CH 2OH | primary | butyl alcohol |
•
Where is butanoic acid found?
Found in fresh and cooked apples, banana, sour cherry, papaya, strawberries, wheat bread, cheeses, butter and coffee. Flavouring agent Butyric acid (from Greek ???????? = butter), also known under the systematic name butanoic acid, is a carboxylic acid with the structural formula CH3CH2CH2-COOH.
How do you convert pKa to Ka?
To create a more manageable number, chemists define the pKa value as the negative logarithm of the Ka value: pKa = -log Ka. If you already know the pKa value for an acid and you need the Ka value, you find it by taking the antilog. In practice, this means raising both sides of the equality to exponents of 10.
Is pKa constant?
pKa is a constant for each conjugate acid and its conjugate base pair. Most biological compounds are weak acids or weak bases. Some acids are polyprotic acids; they can lose more than one proton.
What is the pKa of ch3ch2co2h?
Question: The pKa of propanoic acid (propionic acid), CH3CH2COOH, is 4.87.
What is the common name for 4 chlorobenzoic acid?
4-Chlorobenzoic acid
| Names | |
|---|---|
| Other names p-Chlorobenzoic acidpara-Chlorobenzoic acid | |
| Identifiers | |
| CAS Number | 74-11-3 |
| 3D model (JSmol) | Interactive image |
What is the melting point of 2 chlorobenzoic acid?
Specifications
| Packaging | Glass Bottle |
|---|---|
| Melting Point | 139.0°C to 143.0°C |
| Boiling Point | 285.0°C |
| Quantity | 5g |
| CAS Min % | 97.5 |
What is 3-chlorobenzoic acid used for?
3-chlorobenzoic acid is a monochlorobenzoic acid carrying a chloro substituent at position 3. It has a role as a drug metabolite. It derives from a benzoic acid.
Which butanoic acid is strongest?
- Presence of chlorine changes the acidic strength of acid.
- It is an electron withdrawing group and hence causes polarity.
- The decrease in electron density is responsible for ease of loss of proton.
- Hence, closer the chlorine group, more will be the polarity.
- Therefore, 2-chlorobutanoic acid will be the strongest acid.
Which is stronger acid c6h5cooh or ch3cooh?
Stronger acids have lower pKa value. Due to the presence of benzene ring in benzoic acid, delocalisation of electron makes it more acidic than ethanoic acid but such stabilization is not present in ethanoic acid. …
Is acetic acid weak or strong?
Acetic acid (found in vinegar) is a very common weak acid. Its ionization is shown below. The ionization of acetic acid is incomplete, and so the equation is shown with a double arrow. The extent of ionization of weak acids varies, but is generally less than 10%.
Is lactic acid stronger than acetic acid?
Lactic acid has a lower pKa value (3.86) than acetic acid (pKa = 4.76) and is therefore a stronger acidifier.
Graduated from ENSAT (national agronomic school of Toulouse) in plant sciences in 2018, I pursued a CIFRE doctorate under contract with Sun’Agri and INRAE ​​in Avignon between 2019 and 2022. My thesis aimed to study dynamic agrivoltaic systems, in my case in arboriculture. I love to write and share science related Stuff Here on my Website. I am currently continuing at Sun’Agri as an R&D engineer.