Which is the antisialagogue drug?

An antisialagogue to minimize oral and tracheobronchial secretions may be given: 0.2 mg of glycopyrrolate intravenously or 0.4 mg intramuscularly or 0.4 to 0.5 mg of atropine subcutaneously or intramuscularly.

What does an antisialagogue do?

n. An agent that diminishes or arrests the flow of saliva.

What drugs are Sialogogues?

Salivation may be promoted by using a stimulant: (sialogogue) such as; chewing gums (containing sorbitol or xylitol, not sucrose) diabetic sweets. cholinergic drugs such as pilocarpine, bethanecol, cevimeline or anetholetrithione.

Is atropine an antisialagogue?

Atropine or atropine sulfate carries FDA indications for anti-sialagogue/anti-vagal effect, organophosphate/muscarinic poisoning, and bradycardia. Atropine acts as a competitive, reversible antagonist of muscarinic receptors: an anticholinergic drug.

What is a Vagolytic drug?

Sympathomimetic agents or vagolytic agents Sympathomimetic or vagolytic agents improve conduction through the AVN by reducing vagal tone via muscarinic receptor blockade. They increase heart rate through their vagolytic effects, causing an increase in cardiac output.

What class of drug is neostigmine?

Neostigmine belongs to a class of drugs called Acetylcholinesterase Inhibitors, Peripheral.

What are examples of antisialagogue?

Classic antisialagogues include:

How does glycopyrrolate work for bradycardia?

Glycopyrrolate has been widely used as a preoperative medication to inhibit salivary gland and respiratory secretions. The most frequent reasons for administering anticholinergics include producing an antisialagogue effect, creating a sedative and amnesic effect, and preventing reflex bradycardia.

How long does Robinul last?

Following intramuscular administration, the onset of action is noted in 15 to 30 minutes, with peak effects occurring within approximately 30 to 45 minutes. The vagal blocking effects persist for 2 to 3 hours and the antisialagogue effects persist up to 7 hours, periods longer than for atropine.

What is the use of Sialogogues?

Sialogogues can be used in the treatment of xerostomia (the subjective feeling of having a dry mouth), to stimulate any functioning salivary gland tissue to produce more saliva. Saliva has a bactericidal effect, so when low levels of it are secreted, the risk of caries increases.

What causes Ptyalism?

The most common cause of ptyalism is pregnancy. During the first semester of pregnancy, morning sickness causes many pregnant women to have hypersalivation. Ptyalism can also be a side effect of certain medications or a symptom of underlying diseases.

What is Sialometry?

Sialometry is a measure of saliva flow. Many different techniques have been devised, yet none are perfect. Four major salivary glands and innumerable minor salivary glands generate saliva.

What is atropine used for heart?

The use of atropine in cardiovascular disorders is mainly in the management of patients with bradycardia. Atropine increases the heart rate and improves the atrioventricular conduction by blocking the parasympathetic influences on the heart.

What class of drug is atropine?

Atropine belongs to a class of drugs called Anticholinergic, Antispasmodic Agents.

What is etomidate used for?

Etomidate is a commonly used sedative during rapid sequence intubation (RSI). Septic patients have an increased risk of developing adrenal suppression, which has been associated with increased mortality in some studies. [16] Since etomidate affects cortisol production, its use in septic patients is controversial.

What is Vagomimetic?

[va″go-mi-met´ik] having an effect resembling that produced by stimulation of the vagus nerve.

What medication is given for heart block?

Drugs used to treat AV Heart Block

Drug name Rating Rx/OTC
Generic name: isoproterenol systemic Drug class: vasopressors, adrenergic bronchodilators, catecholamines For consumers: dosage, interactions, side effects For professionals: Prescribing Information
View information about Adrenaclick Adrenaclick Rate Rx/OTC

What is vagus nerve?

The vagus nerve carries an extensive range of signals from digestive system and organs to the brain and vice versa. It is the tenth cranial nerve, extending from its origin in the brainstem through the neck and the thorax down to the abdomen.

What is neostigmine injection used for?

Neostigmine injection is used to treat a muscle disease called myasthenia gravis.

What happens if you give too much neostigmine?

In overdose, depolarization of the endplate caused by excess acetylcholine predominates and leads to depolarization block. The excess acetylcholine at the synapse also causes repeated stimulation of the receptors resulting in the decay time of the endplate potential being prolonged.

Is neostigmine a muscle relaxant?

Like other reversible cholinesterase inhibitors, neostigmine exhibits powerful antimuscle relaxant action. This property of neostigmine is used in anesthesiology for overcoming paralysis of skeletal muscle caused by muscle relaxants.

What is the difference between atropine and glycopyrrolate?

Glycopyrrolate appears to be five to six times more potent than atropine in its antisialogogue effect and also exhibits a selective, though prolonged, effect on salivary secretion and sweat gland activity. It has minimal cardiovascular, ocular and central nervous system effects.

What is the brand name for glycopyrrolate?

Glycopyrrolate is available under the following different brand names: Cuvposa, glycopyrronium, and Robinul.

What are mild sedatives?

The representatives of this group are:

What is glycopyrrolate used to treat?

Glycopyrrolate is used in combination with other medications to treat ulcers in adults and children 12 years of age and older. Glycopyrrolate (Cuvposa) is used to reduce saliva and drooling in children between 3 and16 years of age that have certain medical conditions that cause drooling.

When is glycopyrrolate used?

Glycopyrrolate is used to treat peptic ulcers in adults. It is also used to treat chronic, severe drooling caused by certain neurologic disorders (e.g., cerebral palsy) in children 3 to 16 years of age. This medicine is an anticholinergic.

Why is glycopyrrolate given?

Glycopyrrolate injection is used before and during surgery to lessen mouth, throat, or stomach secretion (eg, saliva, stomach acid), or to prevent heart rhythm problems (during anesthesia, intubation, or surgery), or unwanted effects caused by certain medicines (eg, neostigmine, pyridostigmine).

What does Robinul treat?

Robinul helps to control conditions such as peptic ulcers that involve excessive stomach acid production. Robinul is also used to reduce drooling in children ages 3 to 16 who have certain medical conditions, such as cerebral palsy.

What is Robinul good for?

Robinul Injection (glycopyrrolate) is an anticholinergic that helps to control conditions such as peptic ulcers that involve excessive stomach acid production. The injectable form of Robinul is also used to reduce saliva, nasal, lung, and stomach secretions and to help control heart rate during surgery.

Can you get Robinul over the counter?

Effective treatments are now available to help those with hyperhidrosis. Treatments for hyperhidrosis include over-the-counter antiperspirants, prescription antiperspirants like Drysol (20% aluminum chloride), iontophoresis, pills like glycopyrrolate (Robinul), and surgery.